A SECRET WEAPON FOR NR1-SITE.COM

Utilizing this approach, Kalbaugh et al. assigned affinity and efficacy roles to positions in the LBDs with the NR1 and NR2A NMDAR subunits. In situ mutation of residues in immediate connection with bound ligand afflicted the two efficacy and affinity, even though positions that stabilize the closed cleft conformation with no direct ligand interact